ESR: Single-molecule studies of secondary-active transporters and their environmental dependence | Kapiki

Despoina Kapiki

Ludwig-Maximilans University Munich, Germany

"I am a Medicinal chemist by training and in 2018 I acquired my Chemistry diploma at Aristotle University of Thessaloniki with a specialization chemical synthesis and biosynthesis of natural products of potential antineoplastic activity.

After I obtained my Chemistry diploma, I joined University of Copenhagen’s Masters program in Medicinal Chemistry to further deepen my knowledge into drug design and pharmacology. During my master’s education, I found myself deeply interested in the chemistry of neurotransmission and the use of fluorescent techniques for monitoring protein conformational dynamics. I completed my Master thesis under the supervision of Anders Skov Kristensen on structural studies of glutamate receptors and investigated the mechanisms underlying the pharmacology of antiepileptic drugs or drug candidates with the use of electrophysiology and fluorescence-based techniques.

Through my participation in project 11 in Neurotrans in Prof. Cordes lab I have the opportunity to expand my knowledge in membrane transport by performing single molecule microscopy studies for the elucidation of molecular mechanisms of secondary transporters such as betaine transporter BetP and GABA transporter GAT1.

My participation in Neurotrans is key for accomplishing my ultimate scientific goal; to gain expertise in membrane transport and combine it with my pharmacology and Medicinal Chemistry experience for the identification of CNS drug targets and pharmaceutical development."

E-Mail: Despoina.Kapiki@biologie.uni-muenchen.de

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